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br Introduction Localized degenerative and progressive enlar
2020-02-11
Introduction Localized, degenerative and progressive enlargement of the aortic diameter involves all layers of the vessel wall may ultimately rupture creating a catastrophic cardiovascular event [1,2]. An aneurysm may be located in the thoracic or abdominal aortic wall with different clinical app
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In conclusion our work led to the
2020-02-11
In conclusion, our work led to the characterization of some signalling events of the CysLT1 receptor variants, at several levels, and showed that a punctual serine mutation could alter the response of receptors to cysLTs. Although atopy is a complex phenotype implicating different cell types, mediat
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The pyrrolo benzodiazepines PBDs are a
2020-02-11
The pyrrolo[2,1-][1,4]benzodiazepines (PBDs) are a family of antitumour antibiotics that includes the natural products anthramycin and DC-81. They exert their cytotoxicity by covalently bonding to the exocyclic C2–NH group of guanine residues in the minor groove of DNA through their N10–C11 imine fu
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Models and theories The CPA equation of state
2020-02-11
Models and theories The CPA equation of state is composed predominantly of two parts: physical item and the association item based on the thermodynamic perturbation theory [21], [22], [26], [27]. The physical item is used to represent intermolecular physical interaction, usually representing the SR
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It is well known that the tumor suppressor p
2020-02-11
It is well known that the tumor suppressor p53 plays an important role in regulating the CM-272 and cellular senescence [43,46,48]. For example, FOXO4 could interact with P53, which selectively induced apoptosis in senescent cells [48]. In addition, loss of MECP2 was found to lead to the induction
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br Conclusion and future perspectives
2020-02-11
Conclusion and future perspectives LDL cholesterol-lowering therapy is essential for cardiovascular risk reduction. On the background of a high inter-personal variation of cholesterol synthesis and cholesterol isoprenaline mg the efficacy of cholesterol lowering, both, with statins and with ezet
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As mentioned above of various constitutive models the
2020-02-11
As mentioned above, of various constitutive models, the Chaboche kinematic model was widely used [3,7,[23], [24], [25], [26], [27]]. There exist many significant literature around the Chaboche/Chaboche type plasticity model calibration and its parameter determination methods. Aguis et al. [28] emplo
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Ultrasound is an acoustic wave with
2020-02-11
Ultrasound is an acoustic wave with a frequency >20 kHz that needs a medium to propagate [20]. Accompanied by the spread of an ultrasonic wave, a series of alternating cycles of compression and rarefaction emerge in the liquid medium. During the rarefaction cycle, microbubbles are formed because of
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Cultured cells or mouse lung tissues were harvested
2020-02-10
Cultured cells or mouse lung tissues were harvested and lysed in Radio-Immunoprecipitation Assay (RIPA) buffer (0.05 mol/l Tris–HCl pH 7.4, 0.15 mol/l NaCl, 0.25% deoxycholic acid, 1% NP-40, 1 mmol/l ethylenediamine tetraacetic p2x (EDTA), 1 mmol/l phenylmethylsulfonyl fuoride, 1 μg/ml aprotinin,
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N fowleri enters the host through the
2020-02-10
N. fowleri enters the host through the nasal cavity and travels via the olfactory nerve into the molar concentration calculator where it causes PAM (Visvesvara and Stehr-Green, 1990). The ameba most commonly infects healthy young adults and children and is able to evade the immune system but also el
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In conclusion our data demonstrated
2020-02-10
In conclusion, our data demonstrated that montelukast and pranlukast non-competitively blocked P2Y signaling in several cell systems, but in a relatively nonsubtype-specific manner. The functional antagonism was especially evident at heterologously expressed P2Y1 and P2Y6 receptors, at which IC50 va
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epibatidine br Materials and methods br Results and discussi
2020-02-10
Materials and methods Results and discussion In the present work, we have applied two methodologies, CoMFA and CoMSIA to build 3D-QSAR models. There is no crystal structure available; therefore, an indirect method i.e., a ligand-based approach is the method of choice. The highly active molecul
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Dig-11-utp australia br Introduction Accounting educators an
2020-02-10
Introduction Accounting educators and professional accounting organizations have speculated that advanced placement (AP) may be an effective tool for recruiting high-quality students into accounting education programs (Deines, Bittner, & Eichman, 2012; The Pathways Commission, 2012), and it is no
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This study was aimed to assess a number
2020-02-10
This study was aimed to assess a number of esterase activities, namely erythrocyte AChE, plasma BuChE and BeChE, and serum PON1 towards a number of substrates, as well as the major genetic polymorphisms of BCHE and PON1in a cohort of greenhouse workers exposed to low toxicity pesticides under an int
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The importance of AAE in enhancing
2020-02-10
The importance of AAE3 in enhancing the survival of plants and yeast when confronted with certain environmental stresses has been documented in recent reports. In response to biotic stress such as oxalate-secreting micro-organisms, AAE3 was found to reduce the inhibitory growth effects of the secret
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