• Distribution of DGTS in basidiomycete fungi has been demonst

  2021-05-13

  

  Distribution of DGTS in basidiomycete fungi has been demonstrated to be heterogeneous. In certain fungal taxons, such as Agaricales, Polyporales and Russulales, there are species that synthesize and species that do not synthesize DGTS that belong to the same order or even family (Dembitsky, 1996, Va

• 2449 australia The first group of tests was intended to

  2021-05-13

  

  The first group of tests was intended to evaluate the performance of the GUI initialization. We evaluated the times obtained for different initial GUI models with 1, 2, 3, 5, 10, and 20 components as shown to the user. These sizes were chosen since GUIs (developed within our COTS-based architectures

• The current study had the following

  2021-05-13

  

  The current study had the following 3 aims: Materials and methods Results Discussion Western Europe, USA/Canada, and Australia have traditionally been the areas in which cochlear chir99021 is most common [9], [10]; correspondingly, the most common and well-known validated tests and (re)ha

• Materials and methods br Results br Discussion Microbial pro

  2021-05-13

  

  Materials and methods Results Discussion Microbial production of trans-4Hyp, an added-value amino RK-33 synthesis for pharmaceuticals, offers significant advantages over conventional chemical extraction in economic and environmental aspects. However the low titer and productivity with the ex

• As mentioned above disruption of Tgif in mice is

  2021-05-13

  

  As mentioned above, disruption of Tgif1 in mice is associated with dyslipidemia, and here we investigate the effects of overexpression of TGIF1 on expression of the Npc1l1 gene and markers of intestinal cholesterol absorption. Materials and methods Results Discussion In this study, we soug

• br Dienogest DNG Dienogest is a nortestosterone derivative

  2021-05-13

  

  Dienogest (DNG) Dienogest is a 19-nortestosterone derivative with two special structural changes [Fig. 1a]: [a] At the cabon-17 position there is a cyanomethyl group instead of an ethinyl group; [b] A double bond is present between carbons 9 and 10. DNG is the only progestogen that combines prope

• The highest concentrations from several tens to often

  2021-05-13

  

  The highest concentrations (from several tens to often hundreds or thousands ng/L) are reported in animal farm flush water, and associated runoffs and lagoons in China and in the U.S. Lower concentrations are reported in WWTP influents and effluents. In WWTP influent waters DRO, LNG, NET and PRG hav

• ERR is expressed in several adult

  2021-05-13

  

  ERRγ is expressed in several adult and embryonic tissues but its biological role is still largely unknown [21]. Overexpression of ERRγ in breast cancer correlates with a favorable outcome [22]. In addition, ERRγ has been reported to inhibit the growth of prostate tumor TC-I 15 [23]. In this study w

• Our previous high throughput screening HTS campaign using au

  2021-05-13

  

  Our previous high-throughput screening (HTS) campaign using automated, robust, and sensitive fluorescence based GSK503 assay [10], [11] led to the identification of several EPAC specific inhibitors (ESIs), and was subsequently followed by extensive hit-to-lead optimizations [20], [21], [22], [23],

• Our results indirectly support the combination of resveratro

  2021-05-13

  

  Our results indirectly support the combination of resveratrol and hesperatin treatment for PDN, as this induces GLO1 activity in patients (Xue et al., 2016), as well as metformin, an FDA-approved anti-diabetic treatment, which acts as an MG scavenger to reduce MG levels in type 2 diabetic patients (

• For this study we have used the intermediate affinity mutant

  2021-05-12

  

  For this study we have used the intermediate affinity mutant antigen HEL2× for immunization. However, we have observed a similar defect in the plasmablast differentiation of EBI2-deficient SWHEL Ki16198 over a 10,000-fold affinity range by using WT HEL or the low-affinity mutant HEL3× (data not show

• Autophagy is a degradation pathway existing

  2021-05-12

  

  Autophagy is a degradation pathway existing in all eukaryotic organisms. It is the main system for the degradation of bulk cytoplasmic components in cells (Feng et al., 2014), but it also plays a crucial role in other processes, as immunity (Wileman, 2013), mitochondrial (Dengjel and Abeliovich, 201

• Nowadays colorimetric assay has been applied in detecting

  2021-05-12

  

  Nowadays, colorimetric assay has been applied in detecting DNA MTase activity. Li et al. used DNA modified gold nanoparticles (AuNPs) coupled with enzyme-linkage reactions to detect the activity of methylases [20]. In a previous study, our group presented a label-free colorimetric method, using unm

• Mitochondrial depolarization induced by DHODH inhibition

  2021-05-12

  

  Mitochondrial depolarization induced by DHODH inhibition (Figure 5A) may also contribute to the selective effects of DHODH inhibitors on KRAS mutant cells. If so, the effect may arise more from pro-apoptotic effects of mitochondrial depolarization (Lemasters et al., 1998) than from impaired oxidativ

• These data raised from human tissues suggested a potential

  2021-05-12

  

  These data raised from human tissues suggested a potential link between TGF-β1 signaling and linear invadosome machinery that may explain TGF-β involvement in HCC progression and invasion. Using HCC cultured cells, we confirmed that TGF-β1 stimulation increases the production and secretion of collag

16050 records 659/1070 page Previous Next First page 上5页 656657658659660 下5页 Last page