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Cisplatin based chemotherapy is commonly
2019-05-31
Cisplatin-based chemotherapy is commonly used in adjuvant CCRT, but data on carboplatin-based chemotherapy with radiotherapy is lacking. Khoury et al reported that patients treated with carboplatin-based chemoradiotherapy show worse outcomes. However, the impact on patient comorbidities was not repo
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A dual chamber ICD was
2019-05-31
A dual-chamber ICD was then implanted and the optimal atrioventricular (AV) interval to obtain the lowest PG was adjusted to a sensed PV interval of 70ms/AV pace of 60ms using echocardiography. After 1 week, the LVOT-PG had decreased to 68mmHg (Fig. 2B); by 3 weeks, it had decreased to 26mmHg (Fig.
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The goals of Vision the global initiative to
2019-05-31
The goals of Vision 2020—the global initiative to eliminate avoidable blindness by 2020—include increasing cataract surgical rate and cataract surgical coverage. However, quality must not be sacrificed for quantity. The final visual outcome matters, both to the individual patient and to the communit
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br Acknowledgements br Introduction The chronic myeloprolife
2019-05-30
Acknowledgements Introduction The chronic myeloproliferative neoplasms (MPN) comprise a group of clonal stem cell disorders with a high prevalence of the JAK2 V617F mutation (JAK2+) causing excessive production of mature blood cells. Transformation to acute myeloid leukemia (AML) is seen in 2–
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Of note cases reported by
2019-05-30
Of note, cases reported by Britton et al. and Keung et al. rely on the demonstration of CD7 and TDT along with myeloid markers to classify the blasts as “biphenotypic” [8,9]. Expression of CD3 is not reported by the authors and these cases would not meet the current 2008 WHO criteria for MPAL. Age
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br Conflict of interest br Introduction Garrigue et al repor
2019-05-30
Conflict of interest Introduction Garrigue et al. reported that atrial overdrive pacing reduces the number of sleep calcium channel blocker episodes in pacemaker patients without heart failure [1]. However, this finding has not been replicated in subsequent investigations [2–5], although some
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ldv cost Heat shock facilitates the folding of various prote
2019-05-30
Heat shock facilitates the folding of various proteins as mediated by the HSP family and can stabilize mutant proteins. HS has been reported to facilitate maturation of WT-HERG as well as mutant HERG by activating the HSF family [15]. HSF-1, 2, and 4 were reported to be expressed in humans. HSF-1 is
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Atractyloside Dipotassium Salt In this context in Heather Za
2019-05-30
In this context, in , Heather Zar and colleagues report findings from the first study to assess the accuracy of Xpert MTB/RIF in young children presenting to a primary-care facility with symptoms of pulmonary tuberculosis. Primary analysis was done in 309 children in whom four samples (two induced s
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Illicit financial flight is the unrecorded movement
2019-05-30
Illicit financial flight is the unrecorded movement of capital out of a country in contravention of the regulations of that country. The main mechanism used to undertake this is multinational companies shifting their tax liabilities to sister companies located in low tax jurisdictions, also known as
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br Hospitals in low income
2019-05-30
Hospitals in low-income and middle-income countries receive surgical patients late, and usually when they are critically ill. Consequently, high perioperative mortality and poor surgical outcomes are the unacceptable results of the provision of surgical health care in these countries. However, the
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3-Methyladenine manufacturer All statistical analyses were p
2019-05-29
All statistical analyses were performed using SPSS software (version 15; SPSS Inc., Chicago, IL, USA). Continuous data are expressed as mean (standard deviation) and were analyzed with two independent-samples tests. Chi-square and Fisher\'s exact tests were used for categorical data. The significanc
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SQTS is relatively rare but should be considered
2019-05-29
SQTS is relatively rare, but should be considered if the QT interval is markedly abbreviated and the ST segment is nearly absent with peaked and symmetrical T waves. Thus far, mutations in 5 different genes have been found, but genetic testing remains investigational because these genes account for
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If the patient s coronary artery is very
2019-05-29
If the patient’s coronary artery is very close to the ablation target site, or if the origin of the VT/VPCs cannot be estimated by only the 12-lead ECG, for example, because of a severely deformed thorax or an alteration in the morphology of the VT, the CartoSound® system can be a useful tool for as
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Aggressive osteoblastoma is characterized by epithelioid
2019-05-29
Aggressive osteoblastoma is characterized by epithelioid osteoblasts that are, two to three times larger than conventional osteoblasts, and have abundant eosinophilic cytoplasm, large vesicular eccentric round to oval nuclei with prominent nucleoli. Usually there are rare or absence of mitoses and i
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Introduction Atrial fibrillation AF is the most common cardi
2019-05-29
Introduction Atrial fibrillation (AF) is the most common cardiac arrhythmia managed in clinical practice and the most common arrhythmia requiring hospitalization [1,2]. Thromboembolism occurs with similar incidence, regardless of the form of AF [3,4]. AF management includes anticoagulation to preve
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