• In our study the levels

  2019-06-05

  

  In our study, the levels of BALP, PINP and β-CTx in the serum were significantly (p regardless of their location, thus circulating levels maybe elevated even when skeletal involvement has not emerged. Histomorphological results show that osteolytic and osteoblastic metastases are characterized by si

• br Conflict of interest br Authors contributions br

  2019-06-05

  

  Conflict of interest Authors’ contributions Acknowledgements Introduction Aromatase-Inhibitors (AIs) are commonly used in the treatment of post-menopausal women with a history of hormone receptor-positive breast carcinoma, and have been shown to decrease bone mineral density (BMD) and in

• br Materials and methods br

  2019-06-05

  

  Materials and methods Results Discussion In recent years, it has been revealed that miRNAs are critical members of complex regulatory systems. SNPs or mutations occurring in the miRNA gene region may disturb the properties of miRNAs and result in defect in protein translation of target mRN

• Certainly dynamic interactions between DTCs

  2019-06-05

  

  Certainly, dynamic interactions between DTCs and stromal cholecystokinin receptor within the bone microenvironment disrupt bone homeostasis, which is normally tightly controlled, to fuel metastatic progression [18] (Table 1). For example, it is well established that osteolytic breast cancer DTC-der

• Los v nculos que el

  2019-06-01

  

  Los vínculos que el ensayista conservó con los intelectuales mexicanos fueron profusos y perdurables, en tanto continuaron hasta sus últimos años de vida, aun durante su estadía en la Cuba revolucionaria de principios de los años sesenta. Así, en 1959 inició lo que Ángel Rama denominó el ciclo cuban

• br Conflict of interest br Ethics br Acknowledgment This stu

  2019-06-01

  

  Conflict of interest Ethics Acknowledgment This study was supported by TRF Grants from the Senior Research Scholar Grant, Thailand Research Fund Grant number RTA5580004, and the Higher Education Research Promotion and National Research University Project of Thailand, Office of the Higher Ed

• The importance of the microenvironment for cancer developmen

  2019-06-01

  

  The importance of the microenvironment for cancer development and progression is now widely recognised, but it is worth reminding ourselves that this is a relatively young area of research. Anyone searching PubMed today using the terms “” will find over 22,000 scientific publications, with around 30

• Furthermore permanent cardiac pacemaker implantation may be

  2019-06-01

  

  Furthermore, permanent cardiac pacemaker implantation may be required when severe bradyarrhythmia recurs for a long period. Sympathetic preganglionic neurons innervating the nf-κb pathway may be damaged beyond recovery in such cases [2]. Since placement of new leads immediately after infected lead

• ERS and BrS are thought to represent manifestations

  2019-06-01

  

  ERS and BrS are thought to represent 2 manifestations of the JWSs. Both syndromes are associated with vulnerability to development of polymorphic VT and VF leading to SCD [1–3,15] in young adults with no apparent structural Ion Channel Compound Library disease and occasionally to sudden infant deat

• br La poes a temprana

  2019-06-01

  

  La poesía temprana de Carlos Pellicer (1899–1977) ejemplifica un cambio fundamental en la lírica hispanoamericana. Su obra revela la transición entre el cosmopolitismo ahistórico y exotista y una nueva poesía de conciencia histórica que no solo retoma la historia y la realidad propias de Hispanoam

• Las formas literarias de presentaci n de los textos aqu

  2019-06-01

  

  Las formas literarias de presentación de los textos aquí comentados son distintas: estamos frente a una obra de teatro, dos artículos (o capítulos de libro) y un cuento. El establecimiento de una ‘periodización’ de la historia de la literatura mexicana a partir de cuatro etapas —la prehispánica,

• According to the Disease Early Warning

  2019-06-01

  

  According to the Disease Early Warning System, infectious diseases were widespread during the flood, including cases of cholera, malaria, and polio, consistent with exposure of displaced people to disease imidazoline and conditions of poor hygiene in camps and shelters. Disruption to the management

• In the trial by Arrossi and colleagues in

  2019-06-01

  

  In the trial by Arrossi and colleagues in Argentina, Nanaomycin A health workers randomly allocated to the intervention group delivered self-collection kits to women at their homes during routine visits, instructed women on how to obtain a cervicovaginal sample for HPV testing, and transported the

• La reivindicaci n del m rtir revolucionario El proceso

  2019-06-01

  

  La reivindicación del mártir revolucionario El proceso del egp dio lugar order EPZ015666 consolidar un frente de estudiantes constituido con su línea política, trabajo continuo del estudiantado identificado con ello; respecto a la dirección de esta organización, carecemos de comunicados o publicaci

• To more accurately map the

  2019-06-01

  

  To more accurately map the del(7q) and to search for other submicroscopic aberrations, we performed BAC-based array CGH analysis on BM from the accelerated phase. This confirmed an interstitial deletion in chromosome bands 7q22.1-q35 of maximal size 50.0Mb (Fig. 2D). The minimal region of deletion e

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