• We herein report a patient with dMMR and

  2019-06-15

  

  We herein report a patient with dMMR and MSI-H metastatic gastric cancer who melanocortin 1 receptor responded favorably and durably to PD-1 blockade. This patient, along with the previous two demonstrated by Le et al, are up-to-date the only 3 MMR gastric cancer patients who responded well to PD-1

• br Discussion Primary lymphoma of bone

  2019-06-15

  

  Discussion Primary lymphoma of bone is a rare disease, first described by Oberling in 1928 and he labeled it as reticulum cell sarcoma of bone because of the presence of characteristic reticulin fibers within the lesion [5]. This work was followed by Parker and Jackson and later by Ivin and Bosto

• It is noted that in this study BrS patients

  2019-06-15

  

  It is noted that in this study BrS patients had an abnormality of plasma K+ concentration which has been suggested to be a potential trigger of Brugada Syndrome episodes [11]. In the absence of renal dysfunction, the hyperkalemia may result from an abnormal phenotype in BrS characterized by mutation

• We built and improved on previous models of research capacit

  2019-06-15

  

  We built and improved on previous models of research capacity strengthening and used an integrated approach not only focused on individual researchers or providing technical assistance but also on fostering an institutional environment that hcv protease inhibitor is supportive of safe and ethical sc

• In Richard Walker and colleagues

  2019-06-15

  

  In , Richard Walker and colleagues report the results of a case-control study of risk factors for stroke in Tanzania. Their study makes several important contributions. First, they provide the first information about importance of risk factors for stroke in urban and rural Tanzania, and confirm the

• Evidentemente la institucionalidad junto a la

  2019-06-15

  

  Evidentemente, la institucionalidad, junto butein la paralela retórica de reconciliación, no fue nunca suficiente para hacer de la reinserción del combatiente campesino un proceso fluido en esa sociedad pacificada. Fue, al contrario, un proceso dispar y enredado, lleno de ausencias y silencios. Dent

• Los v nculos que el ensayista conserv con los intelectuales

  2019-06-15

  

  Los vínculos que el ensayista conservó con los intelectuales mexicanos fueron profusos y perdurables, en tanto continuaron hasta sus últimos años de vida, aun durante su estadía en la Cuba revolucionaria de principios de los años sesenta. Así, en 1959 inició lo que Ángel Rama denominó el ciclo cuban

• Introduction Multiple myeloma MM is the most frequent

  2019-06-14

  

  Introduction Multiple myeloma (MM) is the most frequent cancer to involve the skeleton with 80–90% of patients developing bone lesions during their disease course [1]. Myeloma bone lesions are purely osteolytic and are associated with severe and debilitating bone pain, pathologic fractures, hyperca

• Conflict of interest br Introduction Nifekalant hydrochlorid

  2019-06-14

  

  Conflict of interest Introduction Nifekalant hydrochloride was first approved by the Japanese Ministry of Health, Labour and Welfare in 1999 and is now used as a first-line antiarrhythmic drug for refractory ventricular tachyarrhythmias in the country [1]. Nifekalant is a class III antiarrhythmi

• Twenty six of the patients

  2019-06-14

  

  Twenty-six of the 98 patients had an early discontinuation due to recurrence: there were 14 patients with distant ursolic acid and 12 with local recurrence. Most distant metastatic events (71.4%) occurred within the initial two years. Of the other 72 patients with early discontinuation of ET, only

• br Conclusion br Conflicts of interest br Acknowledgments br

  2019-06-14

  

  Conclusion Conflicts of interest Acknowledgments Case report A 56-year-old woman with prior history of dual-chamber permanent pacemaker (PPM) implantation (ELA Medical Symphony DR 2550, ELA Medical, Montrouge, France) for symptomatic complete ipi-145 block presented to the Cardiac Rhyth

• In Philippe B scher and

  2019-06-14

  

  In , Philippe Büscher and colleagues present the first formal assessment under field conditions of the HAT Sero--SeT rapid diagnostic test and compared its diagnostic accuracy with two other current serological tests: CATT and immune trypanolysis (a very sensitive and specific test that requires lab

• br CUANDO EL CUERPO SE HACE ESPACIO El

  2019-06-14

  

  CUANDO EL CUERPO SE HACE ESPACIO El punto en común de estos lienzos es la ausencia de mirada (figuras 3a y 3b). En el primero los ojos están negros, se presentan las dos órbitas vacías; en el segundo están deliberadamente borrados, ya que incluso se puede distinguir por debajo el contorno de los

• That well established data for

  2019-06-13

  

  That well-established data for Sapindaceae toxicity have long existed from clinical experience in Africa and the Caribbean is an important lesson for global health and neurotoxicology. A worldwide understanding of the adverse effects on the nervous system of both naturally occurring as well as synth

• However she had an attack on Day The ECG

  2019-06-13

  

  However, she had an attack on Day 7. The ECG monitor was normal until 4:25 AM (Fig. 1a). ST segment elevation was evident, and the patient experienced chest pain at 4:30 AM (Fig. 1b). ST segment elevations were seen in leads II, III, and aVF on the 12-lead ECG. As sublingual nitroglycerin was ineffe

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