• In an effort to determine whether

  2019-06-28

  

  In an effort to determine whether the primary tumour might be responsible for “fertilising” the bone “soil” ready for the cancer “seed”, we recently found that a hypoxic gene signature, and more specifically the secreted enzyme lysyl oxidase (LOX) was closely associated with bone metastasis, specifi

• Any abnormality causing a loss of function in

  2019-06-28

  

  Any abnormality causing a loss-of-function in the IKs macromolecular complex may lead to adrenergic-induced imbalance in ventricular repolarization currents and consequent QTc prolongation, which is identified based on the defective response of IKs to PKA stimuli due to mutations in KCNQ1 (-G269S, -

• Rulfo emplea un s mil

  2019-06-28

  

  Rulfo emplea un símil para describir la caída de Pedro Páramo, para crear el efecto de desmoronamiento del personaje. El lector o la lectora “oyen” la caída de ese cuerpo. Acompañado por una muerta, Damiana Cisneros, que en la posición de Caronte le invita al mundo de los muertos, Pedro Páramo se de

• En efecto lecturas atentas de estos

  2019-06-28

  

  En efecto, lecturas atentas de estos textos sabrán localizar “lo político” de su empeño signado, más allá de referirse o hacer mención Tempol políticas específicas, encontradas al paso en los lugares que visitan y recorren, o de hablar sobre los personajes políticos que conocen; más allá, pues, de t

• The Cl HCO anion exchanger

  2019-06-28

  

  The Cl−/HCO3− anion exchanger 2 (AE2) is found on cholangiocytes and regulates intracellular pH homeostasis and stimulates bicarbonate secretion. Previous reports have revealed that PBC patients show decreased biliary AE2 expression, and researchers hypothesized that this decrease in AE2 Cathepsin I

• Second political regime does very little

  2019-06-27

  

  Second, political regime does very little to explain differences between countries. Rwanda, Congo (Brazzaville), and Tanzania have very similar child mortality rates (between 40 and 60 deaths per 1000 livebirths in 2014) to South Africa, Botswana, and Namibia despite the former countries being consi

• In this issue of the Shoja et al characterize the

  2019-06-27

  

  In this issue of the , Shoja et al characterize the antimicrobial susceptibility pattern, resistance mechanisms, and typing of carbapenem-resistant (CRAB) isolates obtained from burn patients from a single center in Iran. They found that the rate of CRAB was high (92.5%) among burn patients. The mo

• br Diagnostic criteria Brugada syndrome is definitively diag

  2019-06-27

  

  Diagnostic criteria Brugada syndrome is definitively diagnosed when a type-1 ST-segment elevation is observed in at least 1 right precordial lead (V1 and V2) [23], placed in a standard or a superior position (up to the second intercostal space) (Fig. 1C) [24,25], in the presence or absence of a s

• br Case report A year old man with dilated cardiomyopathy

  2019-06-27

  

  Case report A 68-year-old man with dilated cardiomyopathy [Left ventricular (LV) ejection fraction, 15%] of unknown etiology and nonsustained ventricular tachycardia was referred to our institution. He was prescribed a β-blocker (2.5mg of carvedilol, which was gradually increased to 20mg) and 200

• One day post implant the chest X ray

  2019-06-27

  

  One day post-implant, the chest X-ray showed the pacemaker lead in place within the RV (Fig. 1b, thick white arrow) with appropriate slack (thin black arrow). The pacemaker parameters were satisfactory and the patient was discharged home on the same day. Two weeks after implantation, after returnin

• En las reflexiones sobre la Isla del Encanto

  2019-06-27

  

  En las reflexiones sobre la “Isla del Encanto” de María Teresa Cortés en su aportación titulada “La configuración de la nación en la narrativa histórica puertorriqueña y el sistema de prácticas ecológicas, siglo ” retoma la labor informativa sobre Puerto Rico, hecha por el funcionario español de ori

• br A hallmark of the past

  2019-06-27

  

  A hallmark of the past decade has been the remarkable progress made in reducing maternal and child mortality, an achievement credited in some measure to the Millennium Development Goals. The reduction in child deaths from an estimated 12·7 million under-5 deaths in 1990 to fewer than 6 million dea

• Surgical intervention remains obligatory for hemodynamic ins

  2019-06-27

  

  Surgical intervention remains obligatory for hemodynamic instability, including shock secondary to renal bleeding, complex lacerations, renal pelvic, or ureteral injury, plus certain renovascular conditions. The prolonged warm ischemia that may occur when under renal neoplasty usually results in irr

• Although the CHADS score is useful for evaluating

  2019-06-27

  

  Although the CHADS2 score is useful for evaluating the risk of stroke in NVAF patients, about half of all NVAF patients have a score of 0 or 1 [7]. There are no clear guidelines on whether warfarin should be administered or not, to these patients because the risk of annual incidence of stroke is so

• The mean follow up period was months ICD discharges and

  2019-06-27

  

  The mean follow-up period was 12 months. ICD discharges and ventricular tachycardia (VT) events were recorded by reviewing Holter, exercise ECG tracings, ICD interrogation reports, and clinic visit notes. Sustained VT was considered as VT with a rate of >100 beats per minute and duration of >30s or

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